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Looking ahead to your future

Reimagine your journey

Is it time to rethink your haemophilia journey?

Living with haemophilia can lead to bleeds and joint pain which may affect your daily life. Managing joint pain and reducing the risk of bleeds could help you feel better and enjoy life with fewer restrictions.

Whether it is playing sports with friends, dancing the night away at a concert, hiking or doing everyday activities like walking the dog without concern, these are actions which, for many, can be achieved without being compromised by haemophilia. Understanding how to improve your protection from bleeds and engage in more meaningful conversations with your doctor may help you identify personal goals.

Understanding how to improve your protection from bleeds and engage in more meaningful conversations with your doctor may help you identify personal goals.

The information here is not intended as a substitute for medical advice. If you have any concerns or queries regarding haemophilia, please speak to your doctor, pharmacist, or nurse

Discover how different factor levels affect your protection against bleeds

Understanding levels of protection

When someone without haemophilia (or related bleeding conditions) gets an injury, the trauma triggers a process known as the coagulation (or clotting) cascade. This is a series of reactions in the bloodstream that ends with the blood clotting and the bleeding stopping. This process is known as haemostasis.¹

For people living with haemophilia, one of the clotting factor proteins is partly, or completely missing. This mean that the blood does not clot in the same way and haemostasis takes longer. This can be after an injury and visible, but it can also take place internally with no obvious sign of injury.²

A person's level of protection from bleeds depends on factor levels which represent the amount of clotting factor in the blood. Factor levels also indicate the severity of haemophilia and impact the symptoms you may experience.²

Normalised haemostasis is when levels of factor in the blood needed for blood clotting are the same or nearly the same as in a person without haemophilia.

Factor levels above 40% can be considered to be near that of a person without haemophilia. This could be referred to as moving towards normalised haemostasis.

Reaching these high factor levels, and beyond, may provide increased protection against joint bleeds, impacting joint health, pain and overall wellbeing.³

Speak to your doctor to better understand your factor levels and the impact they may have on your daily activities.

Smith SA, Travers RJ, Morrissey JH. How it all starts: Initiation of the clotting cascade. Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28. PMID: 26018600; PMCID: PMC4826570.
The Haemophilia Society. Understanding Haemophilia. Available at https://haemophilia.org.uk/wp-content/uploads/2017/04/Understanding_haemophilia_WEB.pdf. Last accessed April 2026
Malec, L. Matino, D. Targeting higher factor VIII levels for prophylaxis in haemophilia A: A narrative review. Haemophilia. 2023, 1-11. Available at: https://onlinelibrary.wiley.com/doi/full/10.1111/hae.14866. Last accessed April 2026

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Haemophilia and you

Haemophilia, severity, and bleeding episodes

Living with haemophilia can bring some challenges, like an increased risk of bleeding and joint pain. Learning about your haemophilia is the first step to managing these risks and helping you live life with fewer limitations.